Sustainability, green technologies and chemistry for better living. Can all this be kept under one roof? After the 2018 Industry 4.0 advancement for ‘smarter’ factories, chemistry as a whole was levitated to a new level. Robust tools were manufactured, novel techniques were inculcated and newest compounds were synthesised; giving birth to the Chemistry 4.0. This was not only limited to industrial chemical engineering and factories, but also reinvented the laboratories of the future. This gave a new framework and reformed the way in which the labs and factories would coexist and work for a ‘better’ world ahead. Taking this further, let me take you through some of the most innovative and latest technological updates of the sector.
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Personalized Medicines for Everyone
Not always a pandemic hits the world. And not everytime the virus or disease is generalized or its variant be common in everyone’s body. There may be genetic individualities and uniqueness to a particular disease or disorder in one’s body. Then why should the medicines and treatment be similar or common for all.
(Source: Financial Times)
Personalization is the new digitalization in the field of pharmaceuticals. It is revolutionizing entire industry by offering more targeted and specific therapeutics a patient need. In chemistry 4.0, focused is being made to achieve more efficiency by obtaining huge amount of data and analysis for individual patients. Manufacturing of location-specific medicines and developing user preferred therapeutics can lead to more speedy and easy recovery of patients.
Flow chemistry plays a key role in this aspect of chemistry 4.0 revolution. One-stop solution to the manufacturing of personalized medicines can be enhanced using flow chemistry, which increases the efficiency of drug substance development and thus expediting the production of personalized medicines. Thus, with the wealth of digital tools, Chemistry 4.0 continues to gain momentum by improving efficiency and cost-effectiveness and ultimately providing faster access to more tailored medicines.
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Dominating the Lighting with Chemistry 4.0
Solar powered houses, green houses, photovoltaics, etc etc. Over the last few decades this industry has grown with leaps and has been very dominating since past few years in the sustainable market. Unfortunately, the conventional solar cells lack in efficiency and through-put; making it less demanded amongst the consumers. But, with chemistry 4.0 and the digital revolution coming with it, has enhanced a whole new area of photovoltaics – OPV cells.
(Source: ChemistryWorld)
Organic Photovoltaic (OPV) cells are simply manufactured by combining p- and n- type organic semiconducting polymers and small molecules. This will potentially generate electricity through photovoltaic effect when light radiation corresponding to the energy of the band gap hits the cell. Fine tuning, thinner and light-weight structure and high flexibility makes OPVs a perfect alternative (source) of solar energies of the future. Also, as a power source, OPVs produce the lowest carbon footprint, have shortest energy payback time and at the same time have high power-per-weight ratio than any other solar cell technology.
The most innovative use of this can be using it in a solar-powered smart green-house. In such houses, outer walls are composed of semi-transparent OPVs that absorb light outside the spectrum that plants use for photosynthesis, can provide power for ventilation systems without detriment to plant growth. The potential of OPVs which can be configured with internet of things (IoT) is proving to be revolutionary in chemistry 4.0 applications.
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The Crown of Chemistry 4.0
Semiconductors, AI and IoT. These are the most trending terminologies of the industrial 4.0 revolution. While silicon remained the undoubted superhero of the semiconductor industry of this revolution, there was a need to find its alternative. It was not for its efficiency or cost, but the performance and high-power applications. This is when, Chemistry 4.0 took over the charge.
(Source: ChemistryWorld)
The development of novel, high-quality compound semiconductors and taking industry to another level; was done by a German manufacturer Umicore. It produces ‘Trimethylgallium’ (TMGa). It is innovative, safe and unique in all aspects. Offering most sustainable and ecological production, and minimizing hazards and material-loss; this is the most superior of all manufacturing methods in the industry with almost 100% yield. It is an expert in developing and manufacturing high-purity metals and cutting-edge offerings with quality expertise.
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Transformative Technologies
Whats the most effective ways of learning and practicing to be a pilot? Flight Simulation. A simulation to anyone task makes it effective later on to manufacture it and in turn reduce time of production and preserve the resources too. Incorporating continuous direct compression (CDC) into this process can improve efficiency, reduce waste and minimize batch-to-batch variability.
(Source: ChemistryWorld)
CDC is potentially a flight simulator to manufacture medicinal tablets. It allows the scientist to trial their formulations in silico before they manufacture them in real world. In the manufacturing space it can be the autopilot, providing enhanced feedback and control of the manufacturing operation, using real-time data to maintain control predictively, rather than retrospectively, to understand what could go wrong rather than what went wrong.
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Next-Gen Rapid Diagnostics in Chemistry 4.0
All of us have heard of PCR tests and Rapid Covid-19 tests by now (while some of you may have experienced it). For polymerase chain reaction (PCR) tests, drawback is cost and time. It lacks in both. And drawback with rapid tests is its authenticity and less potential to diagnose asymptomatic patients. This rises the need of more accurate and rapid test system while being effective and authentic.
(Source: ChemistryWorld)
Here’s where chemistry 4.0 jumped in, with its robust new development. Brightline Diagnostics (DX) was formed which focused on manufacture of conjugated polymer nanoparticles (CPNs). With powerful brightness, producing detectable signals even at extremely low levels, a lateral flow device incorporating these nanoparticles can aid detection of asymptomatic Covid-19 carriers. Powered by these innovative probes, Chelsea Technologies’ fluorometric reader can enhance this detection sensitivity further. The result is a highly sensitive and robust diagnostic platform, known as Claritas.
With such Industrial 4.0 and Chemistry 4.0 innovations and technologies persisting together, the future where we can have our diagnostic kits on our quantum technology-based phones is achievable. There will be a whole new era of technology powered by and for chemistry.
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